SCIENTIFIC TEST OF NO-SHIFT-LAG

A scientific trial was conducted in 1996 to determine the efficacy of doses of the homeopathic remedy called No-Shift-Lag in alleviating shift lag.

The design methodology of the trial was a double blind, placebo-controlled crossover.

The setting was the night shift of the Wellington, New Zealand Police Force. The subject group comprised 26 volunteers with experience of night shift work. The study was designed so that feelings of shift lag and mood could be closely monitored.

One tablet was taken at beginning of the shift, one tablet four hours later, and one tablet at the end of the shift. Subjects did not know at the time whether they were taking No-Shift-Lag or the placebo.

The 26 subjects took the remedy or placebo on ten separate night shifts. Randomisation was executed by a mathematician who randomised the trial and labelling treatments so that they could be identified by the experimenters after the research had been completed.

After the shift was completed subjects filled in the survey forms. The questionnaire items related to how the subjects felt at the conclusion of the shift and was the same at the end of every shift and therefore every treatment whether placebo or remedy.

Results


Users taking No-Shift-Lag felt significantly more;
active, alert, awake, responsive and vital,

and significantly less;
foggy, woosy and wanting to sleep.


Variable Number of Cases Mean Mean difference SD SE of Mean Levene's Test, f value Levene's Test, p value
Placebo 95 3.4526 1.420 0.146
No-Shift-Lag 95 3.1979 +0.2547 1.202 0.123 4.099 0.044


Users taking No-Shift-Lag felt significantly less annoyed.
Variable Number of Cases Mean Mean difference SD SE of Mean Levene's Test, f value Levene's Test, p value
Placebo 103 0.5340 0.872 0.086
No-Shift-Lag 101 0.3168 +0.2171 0.706 0.070 6.369 0.012


Users taking No-Shift-Lag felt significantly less bad tempered.
Variable Number of Cases Mean Mean difference SD SE of Mean Levene's Test, f value Levene's Test, p value
Placebo 103 0.43699 0.813 0.080
No-Shift-Lag 101 0.2574 +0.1795 0.658 0.065 6.829 0.010


Users taking No-Shift-Lag felt significantly less discouraged.
Variable Number of Cases Mean Mean difference SD SE of Mean Levene's Test, f value Levene's Test, p value
Placebo 103 0.3689 0.804 0.079
No-Shift-Lag 101 0.2079 +0.1610 0.553 0.055 8.623 0.004


Users taking No-Shift-Lag felt significantly less forgetful.
Variable Number of Cases Mean Mean difference SD SE of Mean Levene's Test, f value Levene's Test, p value
Placebo 103 0.5825 0.924 0.091
No-Shift-Lag 101 0.4257 +0.1568 0.698 0.069 5.291 0.022


Users taking No-Shift-Lag felt significantly less muddled.
Variable Number of Cases Mean Mean difference SD SE of Mean Levene's Test, f value Levene's Test, p value
Placebo 102 0.2843 0.709 0.070
No-Shift-Lag 101 0.1881 +0.0962 0.561 0.056 3.411 0.066


Users taking No-Shift-Lag felt significantly less uncertain.
Variable Number of Cases Mean Mean difference SD SE of Mean Levene's Test, f value Levene's Test, p value
Placebo 103 0.2913 0.695 0.068
No-Shift-Lag 101 0.1782 +0.1130 0.456 0.045 7.451 0.007


Users taking No-Shift-Lag felt significantly less worthless.
Variable Number of Cases Mean Mean difference SD SE of Mean Levene's Test, f value Levene's Test, p value
Placebo 103 0.1650 0.628 0.324
No-Shift-Lag 101 0.0693 +0.0957 0.324 0.032 7.797 0.006


Users taking No-Shift-Lag felt significantly less uneasy.
Variable Number of Cases Mean Mean difference SD SE of Mean Levene's Test, f value Levene's Test, p value
Placebo 103 0.3204 0.0770 0.076
No-Shift-Lag 101 0.1881 +0.1323 0.561 0.056 6.603 0.011


Users taking No-Shift-Lag felt significantly less weary.
Variable Number of Cases Mean Mean difference SD SE of Mean Levene's Test, f value Levene's Test, p value
Placebo 103 1.1650 1.138 0.112
No-Shift-Lag 101 0.9802 +0.1849 0.9802 0.883 6.741 0.010


Users taking No-Shift-Lag felt significantly more peppy.
Variable Number of Cases Mean Mean difference SD SE of Mean Levene's Test, f value Levene's Test, p value
Placebo 103 1.4078 1.167 0.115
No-Shift-Lag 101 1.4752 -0.0675 1.026 0.102 3.942 0.048


Users taking No-Shift-Lag felt significantly more energetic.
Variable Number of Cases Mean Mean difference SD SE of Mean Levene's Test, f value Levene's Test, p value
Placebo 103 1.7476 1.210 0.119
No-Shift-Lag 101 1.8020 -0.0544 1.020 0.101 5.046 0.026


Users taking No-Shift-Lag felt significantly more lively.
Variable Number of Cases Mean Mean difference SD SE of Mean Levene's Test, f value Levene's Test, p value
Placebo 103 1.6019 1.097 0.108
No-Shift-Lag 101 1.8812 -0.2792 0.993 0.099 5.609 0.019


Conclusions

The results of this study tallied with the results from informal testing of No-Shift-Lag, see previous file. Overall the results supported the use of No-Shift-Lag for alleviating shift lag and tiredness when caused by working night shifts.

Author:
Andrew Criglington
Director of Research
Miers Laboratories
Wellington 6038
New Zealand

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